NCSp : Notch Crosstalk Signaling pathway
 |  |
| Selected Pathway | : | NOTCH Signailing Pathway |
| Crosstalk A | Crosstalk B | Tissue Type | Condition Type | Regulation Type | Transcriptional Type | Pubmed ID | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pathway | Uniprot ID | Gene | Pathway | Uniprot ID | Gene | |||||
| Vegf | P15692 | VEGFA | Notch | P49768 | PSEN1 | Acute myeloid leukemia cell | Angiogenesis | Activating | Yes | 23239744 |
| Vegf | P15692 | VEGFA | Notch | P49768 | PSEN1 | Bone marrow endothelial cell line | Angiogenesis | Activating | Yes | 23239744 |
| Vegf | -- | -- | Notch | Q9NR61 | DLL4 | Endothelial cell | Differentiation | Activating | Yes | 23085847 |
| Wnt | Q9UJU2:P35 | LEF1:CTNNB | Notch | O00548 | DLL1 | Mesoderm | Somitogenesis | Activating | Yes | 23602012 |
| Wnt | O14640 | DVL1 | Notch | P46531 | Notch1 | Mesoderm | Somitogenesis | Inhibiting | No | 23602012 |
| Wnt | O14641 | DVL2 | Notch | P46531 | Notch1 | Mesoderm | Somitogenesis | Inhibiting | No | 23602012 |
| Wnt | Q92997 | DVL3 | Notch | P46531 | Notch1 | Mesoderm | Somitogenesis | Inhibiting | No | 23602012 |
| Mapk | Other | MAPK | Notch | P78504 | JAG1 | Squamous cell carcinoma cell | Cancer cells | Activating | No | 16023595 |
| Vegf | P15692 | VEGFA | Notch | O00548 | DLL1 | HUVEC cell | Activating | Yes | 12482957 | |
| Vegf | P35968 | KDR | Notch | -- | -- | Coronary artery endothelial cell | Normal | Unknown | No | 25322777 |
| Hedgehog | P08151 | GLI1 | Notch | Q5TA89 | HES5 | Embryonic stem cell | Normal | Activating | Yes | 21649559 |
| Tgf-beta | P01137 | TGFB1 | Notch | Q9Y5J3 | HEY1 | Marrow cell | Tumor progression | Activating | Yes | 24520074 |
| Vegf | P15692 | VEGFA | Notch | O14672 | ADAM10 | Acute myeloid leukemia cell | Angiogenesis | Activating | Yes | 23239744 |
| Vegf | P15692 | VEGFA | Notch | O14672 | ADAM10 | Bone marrow endothelial cell line | Angiogenesis | Activating | Yes | 23239744 |
| Notch | -- | -- | Hedgehog | Q15465 | SHH | Breast | Cancer | Activating | Yes | 21193018 |