Selected Pathway | : | NOTCH Signailing Pathway |
Crosstalk A | Crosstalk B | Tissue Type | Condition Type | Regulation Type | Transcriptional Type | Pubmed ID | ||||
---|---|---|---|---|---|---|---|---|---|---|
Pathway | Uniprot ID | Gene | Pathway | Uniprot ID | Gene | |||||
Hedgehog | -- | -- | Notch | Q9Y219 | JAG2 | Colon | Colon cancer | Unknown | Yes | 23032367 |
Hedgehog | -- | -- | Notch | Q9Y219 | JAG2 | Breast | Cancer | Activating | No | 21193018 |
Hedgehog | -- | -- | Notch | Q9Y219 | JAG2 | Breast | Cancer | Activating | No | 21151206 |
Hedgehog | P08151 | GLI1 | Notch | Q9UBP5 | HEY2 | Embryonic stem cell | Normal | Activating | Yes | 21649559 |
MTOR | -- | -- | Notch | -- | -- | Breast | Cancer | Inhibiting | No | 23104651 |
Erbb2 | P00533 | EGFR | Notch | P46531 | Notch1 | Many | Cancer | Inhibiting | Yes | 23542173 |
Erbb2 | P04626 | ERBB2 | Notch | P46531 | Notch1 | Many | Cancer | Inhibiting | No | 23542173 |
Erbb2 | P04626 | ERBB2 | Notch | -- | -- | Breast | Cancer | Inhibiting | No | 19344631 |
Erbb2 | P04626 | ERBB2 | Notch | P46531 | Notch1 | Breast | Cancer | Inhibiting | No | 20024517 |
Jak_sat | P40763 | STAT3 | Notch | -- | -- | Glial cell | Development | Activating | No | 15156153 |
TGF_beta | P84022 | SMAD3 | Notch | Q9Y5J3 | HEY1 | HaCaT cell | Activating | No | 23973264 | |
Tgf-beta | -- | -- | Notch | -- | -- | Many | Cancer stem cells | Activating | Yes | 23973264 |
Tgf-beta | -- | -- | Notch | Q14469 | HES1 | T-lymphocyte | Differentiation | Activating | Yes | 22585622 |
Tgf-beta | P84022 | SMAD3 | Notch | Q06330 | RBPJ | T-lymphocyte | Differentiation | Activating | No | 22585622 |
Tcr | -- | -- | Notch | Q06330 | RBPJ | Macrophage | Normal | Activating | No | 20870935 |